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Before Patrick Mahomes laced up his cleats for his 2026-2027 NFL regular-season debut, US prediction markets had already cleared a historic benchmark for the opening week of the season.

Two operators alone – Kalshi and Polymarket – topped the combined $1 billion mark in NFL trading activity over the first six days of Week 1, according to numerous measures this week. During the period, Kalshi recorded NFL volume of $983.4 million, according to DeFi Rate, earning the pole position by a large margin. Mahomes and the Kansas City Chiefs thrashed the Denver Broncos 31-10 on Monday Night Football, capping the largest week for prediction markets ever.

Even before the primetime matchup in Kansas City, it became abundantly clear that the industry would shatter previous marks for weekly activity. The AFC West showdown bolstered the already robust totals. Overall, volume for the week hit a record $15.9 billion, according to Bank of America, up 16% from a week earlier.

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Additionally, the Africa Safer Gambling Week will emphasise the importance of channelisation into legal offerings, with the AiA warning the black market often neglects player protection.

Olabimpe Akingba, head of responsible gaming at pawaTech and AiA board member, said the initiative reflects the association’s push to turn cross-border collaboration within Africa’s iGaming sector into tangible action on player protection.

“At the African iGaming Alliance, we have been committed to moving beyond conversations about collaboration across African jurisdictions towards meaningful action,” she explained.

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